Breaking the Steroid Cycle: New Maintenance Strategies for IgG4-RD...

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2025-12-18 11:04:27 -

Breaking the Steroid Cycle: New Maintenance Strategies for IgG4-RD Patients in 2025

For decades, the "steroid taper" has been a source of anxiety for IgG4-RD patients. While glucocorticoids are incredibly effective at bringing down immediate inflammation, the risk of a flare-up once the dose is lowered remains high—between 30% and 50% in many cohorts. This "yo-yo" effect of inflammation and remission can lead to cumulative organ damage and a poor quality of life. In...

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